In its 2016 edition, the School on Neurotechniques, organised by the CSNII (Convergent Science Network for Biomimetics and Neurotechnology) FET project, will offer an overview on advanced electrical- and light-based recording methods of neuronal excitability, focusing on those that are most relevant for the investigation of neural networks ‘in vitro’ and ‘in vivo’ and for application in neuroprosthetics.